Holzrichter is responsible for leading CME's Global Operations as well as Clearing and Post-Trade Services divisions. She is responsible for the firm's market operations, including the Global Command Center, which is the first point of contact for users of the CME Globex electronic production system. She also oversees the firm's trading floor operations, global market solutions and services, data center and critical infrastructure, global security, and business continuity and crisis management. During her more than 25-year tenure with the company, Holzrichter has taken on increasingly responsible roles, including senior managing director of global operations and managing director of services and technology integration for CME Globex.